Terry Robinson Lab in the department of Pediatrics

Current Research

Cystic Fibrosis

  • Current CF Clinical Research is focusing on an innovative testing strategy for early lung disease surveillance in CF infants.


CT imaging is exquisitely sensitive to detect regional abnormalities associated with lung disease in children. When correlation between changes in CT findings and lung function parameters were compared in children and adults with cystic fibrosis (CF), CT was found to be more sensitive to early changes in lung disease, often preceding any change in global lung function.

We are interested in studying early regional changes in young and older children with chronic lung disease by utilizing quantitative chest CT post-processing.

We are currently studying regional changes in bronchial wall thickness, a finding consistent with airway inflammation, regional bronchiectasis, a sign of significant progressive airway inflammation and airway remodeling, and regional air trapping, a measure of localized airway obstruction from mucus plugging and/or small airway inflammation in infants, toddlers, and older children with CF and other chronic lung diseases.

bronchial tubes

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